Evaluation of the margins of differentiated early gastriccancer by using conventional endoscopy

• 作者: Hajime Takisawa Haruhisa Suzuki Hirokazu Taniguchi Ichiro Oda Satoru Nonaka Seiichiro Abe Shigetaka Yoshinaga Yutaka Saito.
• 来源期刊: 世界胃肠内镜杂志：英文版（电子版）
• 学科: 医学
• 关键词: EARLY gastric cancer CONVENTIONAL ENDOSCOPY Determination of the MARGIN
• 年，卷（期）: 2015,（6）
• 页码范围: 659-664
• 页数: 6页
• 分类号: R

摘要

AIM To evaluate the determination of the marginof differentiated-type early gastric cancers by usingconventional endoscopy.METHODS： We retrospectively evaluated 364 differentiatedearly gastric cancers that were endoscopicallyresected as en-bloc specimens and diagnosed pathologicallyin detail between November 2007 and October2008. All procedures were done with conventionalendoscopes and all endoscopic samples, before and afterindigo carmine dye, were re-evaluated using a digital filingsystem by one endoscopist. We analyzed the incidence oflesions with unclear margins and the relationship betweenunclear margins and relevant clinicopathological findings.RESULTS： The rate of lesions with unclear marginswas 20.6% （75/364）. Multivariate regression analysissuggested that the factors that make the determinationof the margin difficult were normal color, presence ofcomponents of flat area （0-IIb）, a diameter ≥ 21 mm,ulceration, and components of poorly differentiatedadenocarcinoma in the mucosal surface.CONCLUSION： As many as 20% of differentiated earlygastric cancers show unclear margins. Consideration ofthe factors associated with unclear margins may helpendoscopists to accurately determine the margins of thelesion.