Repairing skull defects in children with nano-hap/collagen composites: A clinical report of thirteen cases

• 作者: Bin Luo Chaoqiang Xue Fuzhai Cui Huancong Zuo Jin Zhu Qinglin Zhang Tuoyu Chen Xiumei Wang Yapeng Zhao Yuqi Zhang
• 来源期刊: 临床转化神经医学(英文版)
• 学科: 医学
• 关键词: CRANIOPLASTY CHILDREN BIOMIMETIC bone 3D PRINTING
• 年，卷（期）: 2016,（1）
• 页码范围: 31-37
• 页数: 7页
• 分类号: R726.5

摘要

Objective:To evaluate the clinical results of repairing skull defects with biomimetic bone(nano-hap/collagen composites,NHACs)in children.Methods:Thirteen children with skull defects were treated with NHACs in our hospital.The NHACs molded with the help of a 3D printer were used in the operations.Results:All 13 operations were successful,and patients recovered without infection.Only one patient suffered from subcutaneous hydrops post-operation.The implanted NHACs remained fixed well after 1 year,and their CT HU values raised gradually.Skull shapes of children developed normally.Recovery of neurological and cognitive function was significant.Conclusions:NHAC,chosen to repair skull defects in children,can coexist with normal skull and reduce the negative effects on growth and development.NHAC could be a good choice for children with skull defects.