Effects of the APOE ε4 allele on therapeutic response in Alzheimer’s disease

• 作者: I Chien Yuanhan Yang
• 来源期刊: 临床转化神经医学(英文版)
• 学科: 医学
• 关键词: Alzheimer’s DISEASE APOLIPOPROTEIN E
• 年，卷（期）: sjkxyw_2016,（1）
• 页码范围: 46-49
• 页数: 4页
• 分类号: R749.16

摘要

The apolipoprotein E(APOE)ε4 allelle is a well‐established risk factor for cognitive decline.Racial factors may mitigate its effects.However,APOEε4 has similar effects even among different racial groups.The APOE genotype in patients with Alzheimer’s disease may influence therapeutic decisions.