Treatment of gastric outlet obstruction that results fromunresectable gastric cancer： Current evidence

• 作者: Kiyokazu Nakajima Makoto Yamasaki Masaki Mori Shuji Takiguchi Tomoki Makino Tsuyoshi Takahashi Yasuhiro Miyazaki Yuichiro Doki Yukinori Kurokawa
• 来源期刊: 世界胃肠内镜杂志：英文版（电子版）
• 学科: 医学
• 关键词: GASTRIC OUTLET OBSTRUCTION GASTROJEJUNOSTOMY Endoscopic STENTING GASTRIC cancer Review
• 年，卷（期）: 2016,（3）
• 页码范围: 165-172
• 页数: 8页
• 分类号: R

摘要

Malignant gastric outlet obstruction （GOO） is a commoncondition that results from locally advanced malignanciesin the upper gastrointestinal tract, such aspancreatic, gastric, and other carcinomas. Two typesof procedures for malignant GOO, namely, gastrojejunostomy（GJ） with laparotomy or a laparoscopicapproach and endoscopic stenting （ES）, are currentlyavailable. Although numerous previous reports haveclarified the benefits and drawbacks of each procedure,whether GJ or ES should be used in patients with GOOthat results from gastric cancer who may have a longerlife expectancy than patients with other malignancieshas not been determined. In this review, which focuseson gastric cancer-induced GOO, we analyzed the twosystematic reviews and a meta-analysis that comparedGJ and ES and outlined the current status of GOOtreatment. We also provide an updated review thatincludes laparoscopic GJ. Various data from 13 studiesin one review and 6 studies in another review wereanalyzed. Although the main results of the presentreview indicated that both GJ and ES were efficacioustreatments in patients with GOO that resulted fromgastric cancer, current evidence suggests that GJ maybe the preferable procedure given its good performancestatus and improved prognosis in gastric cancer patients.