Factors associated with visceral fat accumulation in the general population in Okinawa, Japan

• 作者: Akira Hokama Gretchen Parrott Jiro Fujita Kozen Kinjo Kunikazu Hoshino Miwa Higashiarakawa Shingo Arakaki Shuichi Maruwaka Tatsuji Maeshiro Tetsuo Hirata
• 来源期刊: 世界胃肠药理与治疗学杂志：英文版（电子版）
• 学科: 医学
• 关键词: VISCERAL fat accumulation COMPUTED tomography METABOLIC syndrome Alcohol consumption WAIST CIRCUMFERENCE
• 年，卷（期）: 2016,（2）
• 页码范围: 261-267
• 页数: 7页
• 分类号: R589.2

摘要

AIM:To investigate the clinical and biochemical factors associated with visceral fat accumulation in the general population.METHODS:We enrolled 1004 subjects who underwent a medical health checkup between April 2008 and March 2009.The medical health checkup included the following tests:Height,body weight,waist circumference(WC),systolic blood pressure,diastolic blood pressure,urinalysis,blood-cell counts,blood chemistry,electrocardiography,chest radiography,and abdominal computed tomography(CT)for visceral fat accumulation.The patients’medical history and lifestyle factors were collected privately by nurses using a selfadministered questionnaire,and they included questions regarding physical activity,sleep duration,dietary habits,smoking,and alcohol consumption.visceral fat area(VFA)was defined as the sum of the intraperitoneal fat area at the level of the umbilicus with CT density in the range of-150 to-50 Hounsfield units.RESULTS:The mean age and body mass index(BMI)of the study subjects were 57.0 years and 24.4 kg/m2.In both male and females,v FA was significantly andpositively correlated with WC(r=0.532,P<0.01;r=0.612,P<0.01).Subjects with high levels of v FA were primarily male with significantly higher age,height,body weight,BMI,systolic blood pressure(BP),diastolic BP,and hemoglobin in all subjects(P<0.05).A multivariate logistic regression analysis revealed that vF A had a positive relationship with age≥56,BMI≥25 kg/m2,and triglyceride level≥149 in males(P<0.05),whereas it had a positive relationship with age≥58,BMI≥24.4 kg/m2,high-density lipoprotein cholesterol level<40 mg/d L,and current drinking in females(P<0.05).CONCLUSION:These results suggest that gender differences exist in the clinical and biochemical parameters associated with visceral fat accumulation.