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摘要:
The role of arthroscopic partial meniscectomy(APM)in reducing pain and improving function in patients with meniscal tears remains controversial.Five recent highquality randomized controlled trials(RCTs)compared non-operative management of meniscal tears to APM,with four showing no difference and one demonstrating superiority of APM.In this review,we examined the strengths and weaknesses of each of these RCTs,with particular attention to the occurrence of inadvertent biases.We also completed a quantitative analysis that compares treatment successes in each treatment arm,considering crossovers as treatment failures.Our analysis revealed that each study was an excellent attempt to compare APM with non-surgical treatment but suffered from selection,performance,detection,and/or transfer biases that reduce confidence in its conclusions.While the RCT remains the methodological gold standard for establishing treatment efficacy,the use of an RCT design does not in itself ensure internal or external validity.Furthermore,under our alternative analysis of treatment successes,two studies had significantly more treatment successes in the APM arm than the non-operative arm although original intention-totreat analyses showed no difference between these two groups.Crossovers remain an important problem in surgical trials with no perfect analytical solution.With the studies available at present,no conclusion can be drawn concerning the optimal treatment modality for meniscal tears.Further work that minimizes significant biases and crossovers and incorporates sub-group and cost-benefit analyses may clarify therapeutic indications.
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篇名 Controversial role of arthroscopic meniscectomy of the knee:A review
来源期刊 世界骨科杂志 学科 医学
关键词 ARTHROSCOPIC partial MENISCECTOMY Meniscal TEAR KNEE OSTEOARTHRITIS Physical therapy Randomized controlled trial CROSSOVER Bias
年,卷(期) 2016,(5) 所属期刊栏目
研究方向 页码范围 287-292
页数 6页 分类号 R
字数 语种
DOI
五维指标
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研究主题发展历程
节点文献
ARTHROSCOPIC
partial
MENISCECTOMY
Meniscal
TEAR
KNEE
OSTEOARTHRITIS
Physical
therapy
Randomized
controlled
trial
CROSSOVER
Bias
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界骨科杂志:英文版
月刊
2218-5836
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
404
总下载数(次)
1
总被引数(次)
0
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