LAP: the protector against autoimmunity

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2016,（8）
• 页码范围: 865-866
• 页数: 2页
• 语种: 中文
• DOI: 10.1038/cr.2016.70

摘要

The autophagy-related process LC3-Associated Phagocytosis,or LAP,is known to control the degradation of engulfed cells and microorganisms.Now Martinez et al.discover that LAP controls immune responses to dying cells and its inhibition leads to development of Systemic Lupus Erythematosus-like disease.