Lupus pathogenesis: role of IgE autoantibodies

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2016,（3）
• 页码范围: 271-272
• 页数: 2页
• 语种: 中文
• DOI: 10.1038/cr.2016.12

摘要

IgE is commonly known for its role in the Th2 responses, protection against helminth parasites and pathogenesis of allergy.A recent report shows that IgE autoantibodies to dsDNA plays a major role in the pathogenesis of lupus nephritis by exacerbating the interferon-α responses in plasmacytoid dendritic cells.