4-38 DNA Damage in Bone Marrow Mononuclear Cells of Mice Following Total Body Irradiation with Carbon Ions

• 作者: Dang Bingrong Li Wenjian Liu Fang Wang Zhuanzi Wei Wei
• 来源期刊: 中国科学院近代物理研究所和兰州重离子研究装置年报：英文版
• 学科: 物理学
• 年，卷（期）: 2016,（1）
• 页码范围: 156-157
• 页数: 2页
• 分类号: O4

摘要

Among the many special factors in the space environment,space radiation especially high energy heavy ion radiation is widely regarded as one of the crucial factors that hazard the health and safety of astronaut.It is well known that biological effects of radiation are dependent on the linear-energy-transfer(LET)of the emergent beam.Heavy ions have high LET and could induce complex and clustered DNA damage,which is more difficult to be repaired than individual lesions and is even irreparable.