NgAgo: an exciting new tool for genome editing

• 来源期刊: 科学通报（英文版）
• 年，卷（期）: 2016,（14）
• 页码范围: 1074-1075
• 页数: 2页
• 语种: 中文
• DOI: 10.1007/s11434-016-1117-8

摘要

Site-directed DNA endonucleases are powerful tools for genome editing.When introduced into ceils,these systems can bind to a target DNA sequence in the genome and create a DNA double-strand break (DSB),the repair of which leads to varied DNA sequence modifications.