4-60 Study on Protein Marker of Hepatotoxicity Induced by Iron Ion Radiation in Mice

• 作者: Li Hongyan Zhang Hong
• 来源期刊: 中国科学院近代物理研究所和兰州重离子研究装置年报：英文版
• 学科: 物理学
• 年，卷（期）: 2016,（1）
• 页码范围: 186-186
• 页数: 1页
• 分类号: O4

摘要

It is important to determine whether exposure to cosmic radiation induces disease or toxicity in astronauts and space travellers[1].In this investigation,we used a comparative proteomics approach based on a 2-DE reference map to detect alterations in protein expression in the serum of Swiss–Webster mice following exposure to iron ion radiation(IIR),and to identify biomarkers of liver toxicity.The results reveal the underlying molecular mechanisms of liver disease or toxicity following exposure to IIR.