In order to make sure that the tumor is irradiated by a uniform and adequate dose and the surrounding tissues are damaged as little as possible,we need to monitor and measure the irradiation dose in real time.The dose monitoring probe of the beam intensity monitoring system in the deep-seated tumor therapy is an integral ionization chamber,its’output current signal is proportional to the beam intensity.The output signal of the ionization chamber is less than 1 A.In order to measure the weak current signal,a new current to frequency converter has been developed.