In this paper, we conduct research on the construction of the ecological civilization model under the regional harmonious development background. Our country has achieved by the planned economy to basic socialist market economy important historic transformation, regional management system after several changes, the government organization adjustment for many times, in both market and government forces to promote the regional cooperation mechanism is increasingly rich, mutual assistance and support mechanism gradually complete, a variety of the mechanisms as we pattern is emerging. The current regional harmonious development must be based on general regional interests coordination, strive to build a regional comparative advantage into full play, regional gap control in a reasonable scope, area equal basic public services, strengthen market integration, effective utilization of the resources and ecological environment protection and improve the dynamic combination of fi ve goals. Under this basis, we propose the new perspectives on the issues that are meaningful.