In this paper, we conduct research on the infl uence of macroeconomic management of the enterprise from the perspective of general analysis of inertial. Enterprise economic management and economic development is the relationship between the local and global, between enterprises is global economic development, guide and lead the enterprise smooth and orderly economic management; Enterprise economic management is local while the collaboration and auxiliary enterprise economic development. Only under the guidance of holistic view of the enterprise economic development, the enterprise economic management was able to fi nd right direction. Actively explore peopleoriented human resources management system, new measures. People-oriented human resources management of new system, new initiatives, and throughout its intrinsic nature factors to respect, understanding, and give full play to the role of the basic guiding ideology. Our research provides the new paradigm.