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摘要:
Vaginitis is one of the most recurrent conditions that afflict women and require medical care. Vulvovaginal candidiasis (VVC) is frequently related to vaginal carriage of Candida albicans, an opportunistic polymorphic fungus, which colonizes the human skin, the mucosa and the reproductive tract. Actually, standard treatments to counteract vaginitis include several topical and oral treatments. The aim of this study was to evaluate the efficacy of a new biguanide compound, polyhexamethylene biguanide (PHMB) in avaginal solution, in women affected by vaginal candidiasis. For this reason, 40 women showing the symptoms previously ascribed to vaginal candidiasis were recruited and treated with a single PHMB dose of vaginal solution. After a single dose of treatment, 80% of them had a complete resolution of the fungal infection;furthermore, all of them reported clinical benefits, statistically significant reduction in both clinical signs and symptoms of candidiasis and a score’s reduction of 50%.
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篇名 Polyhexamethylene Biguanide in Vaginal Solution Is Effective in the Treatment of Vulvovaginal Candidiasis: A Pilot Study
来源期刊 妇产科期刊(英文) 学科 医学
关键词 Polyhexamethylene BIGUANIDE VULVOVAGINAL CANDIDIASIS Candida ALBICANS Infection BIGUANIDE ANTISEPTIC
年,卷(期) 2017,(1) 所属期刊栏目
研究方向 页码范围 7-15
页数 9页 分类号 R73
字数 语种
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节点文献
Polyhexamethylene
BIGUANIDE
VULVOVAGINAL
CANDIDIASIS
Candida
ALBICANS
Infection
BIGUANIDE
ANTISEPTIC
研究起点
研究来源
研究分支
研究去脉
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相关学者/机构
期刊影响力
妇产科期刊(英文)
月刊
2160-8792
武汉市江夏区汤逊湖北路38号光谷总部空间
出版文献量(篇)
642
总下载数(次)
0
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