Studies on the Hypoglycemic and Hypolipidemic Effects of <i>Nelumbo nucifera</i>Leaf in Long-Evans Rats

• 作者: Abida Sultana Amdadul Huque Dipa Islam Evena Parvin Lipy Liton Chandra Mohanta Md. Nazibur Rahman Sheuly U. K. Prodhan
• 来源期刊: 糖尿病(英文)
• 学科: 医学
• 关键词: Diabetics HYPOGLYCEMIA HYPOLIPIDEMIA ALLOXAN MONOHYDRATE
• 年，卷（期）: 2017,（3）
• 页码范围: 55-70
• 页数: 16页
• 分类号: R73

摘要

The study was carried out to evaluate the hypolipidemic and hypoglycemic effect of Nelumbo nucifera leaf powder. In rats, hyperlipidemia was induced by feeding High Fat Diet (Lab diet: Dalda: Coconut oil = 4:3:1) and type 2 diabetes was built inside by injecting Alloxan. The sample N. nucifera leaf powder was added in different percentages with the regular Lab Diet for 21 days feeding. In case of hyperlipidemia developed groups, feeding of Nelumbo nucifera leaf powder at, 30% (70% Lab diet + 30% Sample), 20% (80% Lab diet + 20% Sample) and 10% (90% Lab diet + 10% Sample) showed varied but in a nutshell significant (p Nelumbo nucifera leaf powder for 21 days resulted significant decrease in the blood glucose levels of alloxan-induced diabetic rats. Both the percentages of Nelumbo nucifera leaf powder having 20% with 80% Lab Diet and 10% with 90% Lab Diet significantly (p Nelumbo nucifera powder was found to be exerted to the more prominent effects in lowering the blood glucose level. Nelumbo nucifera leaf powder had 75% efficacy rate in lowering the blood glucose level in comparison to the drug control group treated with glibenclamide which was found with the decreasing capability up to 66%. Although not significant, it, based on the data, can be stated that the sample is endowed with the quality of decreasing capability of body weight. Thus, results of the experimental study reveal that the leaf of Nelumbo nucifera has potent hypoglycemic and hypolipidemic properties.