Efficacy of Intra-Cystic Methotrexate Injection in Management of Benign Persistent Ovarian Cysts

• 作者: Adel El Gergawy Ahmed El Halwagy Ayman S. Dawood Mohamed E. Kabeil
• 来源期刊: 妇产科期刊(英文)
• 学科: 医学
• 关键词: Simple CYST METHOTREXATE Ultrasound Guided ASPIRATION RECURRENCE
• 年，卷（期）: fckqkyw_2017,（1）
• 页码范围: 51-60
• 页数: 10页
• 分类号: R73

摘要

Aim: To evaluate and compare the efficacy of methotrexate injection in management of persistent simple ovarian cyst versus the use of transvaginal ultrasound aspiration alone. Patients and Methods: This randomized controlled study was conducted at Tanta University Hospitals in the period from April 1, 2016 to October 31, 2016. Patients were randomly allocated into two groups;each group has 25 patients with benign persistent simple ovarian cyst. Group I: Patients were subjected to transvaginal aspiration of the cyst. Group II: patients were subjected to methotrexate injection inside the cyst. Patients in both group were followed up at 1, 3, 6 months after procedure for the recurrence and occurrence spontaneous pregnancy. Results: The mean age in group I was 28.8 years, and the mean age in group II was 26.52 years with non-significant difference. Also there was non-significant difference between both groups regarding size of the cyst. No case recorded to have a cyst recurrence in group II and four cases in group I within six months with significant difference (P value 0.037), and there was non-significant differences as regard the pregnancy rate and complications. Conclusion: Transvaginal intra-cystic methotrexate injection is a safe and effective choice for management of persistent simple benign ovarian cyst.