Evidence based review of negative pressure wound therapy

• 作者: Adriana C Panayi Dennis P Orgill Tripp Leavitt
• 来源期刊: 世界皮肤病学杂志
• 学科: 医学
• 关键词: Negative PRESSURE WOUND THERAPY Chronic WOUNDS Microdeformational WOUND THERAPY Vacuum assisted CLOSURE PRESSURE ULCERS
• 年，卷（期）: 2017,（1）
• 页码范围: 1-16
• 页数: 16页
• 分类号: R

摘要

Vacuum-assisted closure,sometimes referred to as microdeformational wound therapy or most commonly negative pressure wound therapy(NPWT),has significantly improved wound care over the past two decades.NPWT is known to affect wound healing through four primary mechanisms(macrodeformation,microdeformation,fluid removal,and alteration of the wound environment)and various secondary mechanisms(including neurogenesis,angiogenesis,modulation of inflammation,and alterations in bioburden)which are described in this review.In addition,the technique has many established uses,for example in wound healing of diabetic and pressure ulcers,as well as burn and blast wounds.This therapy also has many uses whose efficacy has yet to be confirmed,for example the use in digestive surgery.Modifications of the traditional NPWT have also been established and are described in detail.This therapy has various considerations and contraindications which are summarized in this review.Finally,future perspectives,such as the optimal cycling of the treatment and the most appropriate interface material,are touched upon in the final segment.Overall,despite the fact that questions remain to be answered about NPWT,this technology is a major breakthrough in wound healing with significant potential use both in the hospital but also in the community.