A Patient with Post Infectious Immune Mediated Neuropathy (Miller Fisher Syndrome)

• 作者: Azad Esack Sharlene Sanchez
• 来源期刊: 临床医学国际期刊(英文)
• 学科: 医学
• 关键词: Miller Fisher Anti-Ganglioside DEMYELINATING IMMUNE MEDIATED
• 年，卷（期）: 2017,（3）
• 页码范围: 123-127
• 页数: 5页
• 分类号: R73

摘要

The Miller Fisher variant is an uncommon but well known syndrome being described as a triad of areflexia, ataxia and complex ophthalmoplegia. It is characterized by antibodies against myelin that affects peripheral nerves, extraocular muscles and Schwann cells. Anti-ganglioside antibodies have been recognized in disease pathogenesis and decreasing antibody production is the mainstay of treatment. The course is usually benign with improvement after immunomodulation. This case report describes the approach to a patient suspected of having a demyelinating disorder. It delineates the subsets of immune mediated neuropathies in evaluating the diagnosis and emphasizes the need for early therapeutic intervention in achieving a good clinical outcome.