Three-dimensional radiation dosimetry using polymer gel and solid radiochromic polymer: From basics to clinical applications

• 作者: Leighton Warmington N Gopishankar Yoichi Watanabe
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: 光计算断层摄影术 三维的剂量测量 稳固的 radiochromic 聚合物 磁性的回声成像 聚合物胶化
• 年，卷（期）: 2017,（3）
• 页码范围: 112-125
• 页数: 14页
• 分类号: R73

摘要

Accurate dose measurement tools are needed to evaluate the radiation dose delivered to patients by using modern and sophisticated radiation therapy techniques. However, the adequate tools which enable us to directly measure the dose distributions in threedimensional(3D) space are not commonly available. One such 3D dose measurement device is the polymerbased dosimeter, which changes the material property in response to radiation. These are available in the gel form as polymer gel dosimeter(PGD) and ferrous gel dosimeter(FGD) and in the solid form as solid plastic dosimeter(SPD). Those are made of a continuous uniform medium which polymerizes upon irradiation. Hence, the intrinsic spatial resolution of those dosimeters is very high, and it is only limited by the method by which one converts the dose information recorded by the medium to the absorbed dose. The current standard methods of the dose quantification are magnetic resonance imaging, optical computed tomography, and X-ray computed tomography. In particular, magnetic resonance imaging is well established as a method for obtaining clinically relevant dosimetric data by PGD and FGD. Despite the likely possibility of doing 3D dosimetry by PGD, FGD or SPD, the tools are still lacking wider usages for clinical applications. In this review article, we summarize the current status of PGD, FGD, and SPD and discuss the issue faced by these for wider acceptance in radiation oncology clinic and propose some directions for future development.