Expression and Significance of IL-6 and bFGF in Human Tongue Squamous Cell Carcinoma

• 作者: Ju-Hua Hou Juan Duan Wen-Jiang Zhang Xiao-Ju Hou Yuan-Yue Liu Zheng-Bing He
• 来源期刊: 癌症治疗(英文)
• 学科: 医学
• 关键词: TONGUE SQUAMOUS Cell Carcinoma IL-6 BFGF TISSUE ARRAY
• 年，卷（期）: 2017,（2）
• 页码范围: 210-215
• 页数: 6页
• 分类号: R73

摘要

Objective: To detect the expression and pathological significances of Interleukin-6 (IL-6) and basic fibroblast growth factor (bFGF) in tongue squamous cell carcinoma (TSCC). Methods: A tissue array was analyzed immunohistochemically. The expression levels of IL-6 and bFGF in tissues were recorded semi-quantitatively. Results: The positive expression of IL-6 in normal, benign tumor, and carcinoma groups was 12.50% ± 5.575%, 39.00% ± 1.41%, 77.26% ± 17.07% respectively, and the expression among the three groups showed significant differences (P P P Conclusion: It indicates that combining immunohistochemical examination of IL-6 and bFGF has an important reference value on the pathological diagnosis of tongue squamous cell carcinoma.