Vitreomacular Traction Post Intravitreal Bevacizumab for Age Related Macular Degeneration

• 作者: Gyasi E. Micheal Harriman Ayodele Hassan O. Adekunle Oderinlo Olufemi Ogunro Adunola Okonkwo N. Ogugua Oluyadi B. Fatai Ulaikere Mildred
• 来源期刊: 眼科学期刊(英文)
• 学科: 医学
• 关键词: Vitreomacular TRACTION Vitreomacular Adhesion INTRAVITREAL Injection Optical COHERENCE Tomography AVASTIN Age Related MACULAR DEGENERATION
• 年，卷（期）: 2017,（2）
• 页码范围: 138-144
• 页数: 7页
• 分类号: R77

摘要

Purpose: To report the significant worsening of Vitreomacular Traction (VMT), following the intravitreal injection of Bevacizumab (Avastin) in an Age Related Macular Degeneration (AMD) eye;thereby raising the awareness of this possibility. Method: Retrospective observational case report. Results: After 3 monthly doses of intravitreal injection of 1.25 mg/0.05 cc bevacizumab for treatment of AMD, a post injection OCT revealed the presence of VMT and an increased central macular thickness (CMT) by additional 268 microns compared to pre injection levels. Conclusion: Worsening of VMT and increase in CMT following injection of intravitreal drugs can occur. This VMT worsening effect of intravitreal injections is under recognized. It demands greater attention since it is seen with a new common route of ocular drug delivery and may be responsible for cases of pharmacological failure.