Retinal Damage of Hemoglobinopathies in Adults: About 181 Cases in Campus-Teaching Hospital of Lomé

• 作者: Koffi Didier Ayena Kokou Vonor Komi Patrice Balo Kossi Brice Dzidzinyo Nidain Maneh
• 来源期刊: 眼科学期刊(英文)
• 学科: 医学
• 关键词: HEMOGLOBINOPATHY SICKLE Cell RETINOPATHY Adult Lomé
• 年，卷（期）: 2017,（3）
• 页码范围: 153-157
• 页数: 5页
• 分类号: R5

摘要

Aims: To study the frequency of sickle cell retinopathy and its severity. Material and Methods: Retrospective study over a period of 3 years (July 2013 thru June 2016) of cases of adults over 18 years old sent by the Hematology Department of the Campus-Teaching Hospital of Lomé in the context of a sickle-cell disease check-up. The parameters studied were age, sex, genotype, examination of the fundus by the Goldmann lens. The classi-fication after the fundus was in non-proliferative retinopathy and in 5 proliferative stages according to Goldberg’s classification. Results: Hundred and eighty-one patients were included with an average age of 29.39 ± 9.84. The sex ratio was 0.72 in favor of female. The SC genotype was 50.3%;SS 37.6%;CC 11% and SF 1.1%. Sickle cell retinopathy was found in 22.7% of patients, among which 14.4% were proliferative and 8.3% non-proliferative. Seventy-three percent of patients with proliferative retinopathy were SC genotype, 23% SS and 3% CC genotype. Among SC patients, 20.9% had proliferative retinopathy;8.8% SS;and 5% CC. Fifty percent of patients with proliferative retinopathy had Goldberg’s stage ≥ 3. Conclusion: We found 22.7% of sickle cell retinopathy which proliferative form was strongly represented by the SC genotype.