This study aimed to investigate the effect of social and economic differences between importer and exporter countries on trade flows of Sesame seed product. The analysis was carried out by estimating the gravity model. The sample covered a total of 14 countries for the period from 1997 to 2009. The results showed that the social and economic differences between countries have a significant and positive or negative effect on Sesame seeds trade. Furthermore, we found that the same language, distance and sesame production in export country have positive effect for the sesame export from Sudan.