Biological effect and molecular mechanism study of biomaterials based on proteomic research

• 来源期刊: 材料科学技术（英文版）
• 年，卷（期）: 2017,（7）
• 页码范围: 607-615
• 页数: 9页
• 语种: 英文

摘要

Along with the role transformation of biomaterials from bioinert substitute to regenerative inducer,the biological effect and mechanism of material-organism interaction become more important.Since most of animal tests and cellular experiments stay on the phenomenon description instead of mechanism interpretation,the development of proteomics technologies provides a golden opportunity to uncover the molecular interaction mechanism between biomaterial-organism on whole scale.This review summarizes current application of proteomics in biological effect and mechanism study of biomaterials,and discusses the development and challenges for future studies.