Schwannomas are neurogenic tumors that arise from the Schwann ceils of the nerve sheath,also called shwann cell tumor.More common in patients with 30 to 40 years old.This tumor always occurs in the septum,maxillary sinus,ethmoid sinus,etc.The Schwannoma is rare in sphenoid sinus with only sporadic cases at home and abroad.Our institute received and cured a sphenoid sinus nerve sheath tumor patient,the preoperative misdiagnosis is the sphenoid sinus cyst and the postoperative pathological diagnosis is sphenoid sinus nerve sheath tumor.Therefore,we introduce a case of the sphenoid sinus nerve sheath tumor misdiagnosed as the sphenoid si nus cyst.