鼻腔鼻窦滑膜肉瘤的发病机制及研究进展

• 作者: 周政 苗刚勇
• 来源期刊: 临床耳鼻咽喉头颈外科杂志
• 学科: 医学
• 关键词: 鼻腔,鼻窦 滑膜肉瘤 发病机制 发展
• 年，卷（期）: 2017,（7）
• 所属期刊栏目: 综述
• 页码范围: 571-574
• 页数: 4页
• 分类号: R739.6
• 语种: 中文
• DOI: 10.13201/j.issn.1001-1781.2017.07.022

摘要

Synovial sarcoma of the nasal cavity and sinus are rare,comprise less than 0.1％ of all soft tissue malignancies.Synovial sarcoma is a malignant mesenchymal tumor with variable epithelial differentiation,which is defined by the presence of a specific chromosomal translocation that generates SS18-SSX fusion oncogenes.The treatment include surgery,radiotherapy,chemotherapy.As the delicate anatomy of the nasal cavity and sinus limits the ability to obtain wide surgical margins.This maybe the reason why there is a higher local recurrence rate and worse disease-specific survival in head and neck sarcomas compared to other sites.