Mediated electrochemical oxidation of unactivated C-H bonds in high-chemoselective and large-scale manner

• 来源期刊: 科学通报（英文版）
• 年，卷（期）: 2017,（17）
• 页码范围: 1167-1168
• 页数: 2页
• 语种: 英文

摘要

The direct functionalization of C-H bonds has been one of the fundamental and challenging fields in organic chemistry.In contrast with traditional chemical oxidation (mostly involving strong oxidants and expensive metal complex) and photo-chemical oxidation,electrochemistry accomplishing redox processes,by employing electron as a "green reagents",provides a practical and sustainable alternative strategy to effect such transformations.In view of the fact that unactivated methylene and methane have high redox potentials and oxidative degradation of other functional groups and solvents is then more likely to occur before the desired C-H oxidation in direct electrochemical process [1,2],a mediated electrochemical oxidation with relatively lower energy consumption compared was a promising solution to facilitate the chemoselective C-H functionalization [3].