甲状腺炎性肌纤维母细胞瘤1例

• 作者: 刘庚勋 刘阳云 常恩格 张彩霞 张纪帅 曹杭 江文 赵花香 邬书本 陈琼
• 来源期刊: 临床耳鼻咽喉头颈外科杂志
• 学科: 医学
• 关键词: 炎性肌纤维母细胞瘤 甲状腺
• 年，卷（期）: 2017,（9）
• 所属期刊栏目: 病例报告
• 页码范围: 720-721
• 页数: 2页
• 分类号: R739.6
• 语种: 中文
• DOI: 10.13201/j.issn.1001-1781.2017.09.020

摘要

Summary A elderly woman patient,with a unclear boundary,solid,smooth surface,moderately active mass that estimated 0.4 cm at its greatest diameter in the left lobe of thyroid.Ultrasonography revealed a hypoechoic mass in the left lobe and Computed Tomography showed a 38 mm× 25 mm× 23 mm oval lesion with uniform density in the left lobe also.The surgical findings revealed tumor located in the inner side of left thyroid lobe near the isthmus,with unclear boundary.Pathological examination showed unclear boundaries between thyroid and tumor,the tumor cells attack into the muscle tissue,braided/ fascicles spindle shaped or star shaped myofibroblasts cells in the tumor area with myxedema inflammatory background and the lesion did not have any mitotic figures.Immunohistochemical analysis indicated that the spindle cells were positive for Vim,ACT,SMA,Bcl2 and ClyD1,and focal lesion histiocytes showed focal positive for CD68,CK and S-100,but negative for DES,Mgo,CD99,CD34,CD117,IgG4,ALK-1.The pathological diagnosis supports inflammatory myofibroblastic tumor of thyroid.Imaging and immunohistochemistry and others are useful in differential diagnosis.