滤泡性淋巴瘤预后因素评估及个体化危险分层研究进展

• 作者: 张扬 胡春宏
• 来源期刊: 临床血液学杂志
• 学科: 医学
• 关键词: 滤泡性淋巴瘤 预后因素 个体化 危险分层
• 年，卷（期）: 2017,（7）
• 所属期刊栏目: 综述
• 页码范围: 568-571
• 页数: 4页
• 分类号: R733.4
• 语种: 中文
• DOI: 10.13201/j.issn.1004-2806.2017.07.023

摘要

Follicular lymphoma (FL) is a common and indolent lymphoma.The recently studies show that FL displays heterogeneity for clinical process and biological prognostic biomarkers.A large class FL patient is asymptomatic with indolent course which are vulnerable to the toxic chemo-therapies.However,a subset of FL develop chemo-resistance and undergo a transformation to aggressive lymphoma.These subtypes are needed for new therapies and alternative approaches.Following new biomarkers had been discovered,previous clinical prognostic indices for FL become limited.In this review,we introduce the clinical prognostic index in FL and novel prognostic markers for evaluating poor risk.A useful incorporation both clinical and molecular determinants for the risk stratification of FL will help to identify high-risk FL at diagnosis and choose rational targeted therapies.

作者信息

序号	姓名	单位	发文数	被引次数	H指数	G指数
1	胡春宏		90	494	12.0	17.0
2	张扬		10	39	4.0	6.0