头颈鳞状细胞癌的免疫治疗

• 作者: 严晓菊 张欣欣 徐开伦
• 来源期刊: 临床耳鼻咽喉头颈外科杂志
• 学科: 医学
• 关键词: 头颈鳞状细胞癌 免疫逃逸 细胞因子 免疫检查点抑制剂 肿瘤疫苗
• 年，卷（期）: 2017,（13）
• 所属期刊栏目: 综述
• 页码范围: 1050-1056
• 页数: 7页
• 分类号: R739.6
• 语种: 中文
• DOI: 10.13201/j.issn.1001-1781.2017.13.024

摘要

The Head and neck squamous cell carcinoma(HNSCC) is a group of heterogeneous diseases.Patients with HNSCC demonstrate poor prognosis and survival time with standard therapy,especially in patients with advanced HNSCC.Recurrence and metastasis have not yet been effectively controlled.The immune profile in HNSCC,whether caused by carcinogen exposure or human papillomavirus(HPV),showed significantly immunosuppression.With the understanding of the complex interaction between tumor and immune system and immune escape mechanism of HNSCC,new immunotherapies have been generating.This article will summarize the immunological mechanism and immune therapy of HNSCC currently.

作者信息

序号	姓名	单位	发文数	被引次数	H指数	G指数
1	张欣欣		20	87	5.0	8.0
2	严晓菊		1	0	0.0	0.0
3	徐开伦		1	0	0.0	0.0