Assessment of Renal Biomarkers of Renal Function in Commercial Automobile Workers in Benin City, Edo State, Nigeria

• 作者: Alaba Michael Emmanuel Babatunde Ishola Gabriel Adejumo Gregory Ashimedua Uchuno Kehinde Olawunmi Awelogun Kingsley Ifeanyichukwu Omosor Oladimeji Nasiru Abdulrahman Uchechukwu Dimkpa
• 来源期刊: 肾脏病(英文)
• 学科: 医学
• 关键词: AUTOMOBILE Workers RENAL Biomarkers BENIN City NIGERIA
• 年，卷（期）: 2018,（1）
• 页码范围: 18-28
• 页数: 11页
• 分类号: R73

摘要

Background: Blood-urea nitrogen, creatinine, uric acid and electrolytes are important biomarkers of renal function which could be considered as suitable prognostic indicators of renal dysfunction. Aim: The aim of this work was to assess renal biomarkers of renal function in commercial automobile workers in Benin City, Edo State, Nigeria. Methodology: A total of 158 males within the ages of 18 - 60 years participated in this study, 50 of which are control subjects. They were recruited for this study from various workshops in Benin City, while controls are unexposed volunteers. Results: It was observed that serum uric acid, urea, creatinine, chloride and bicarbonate levels in all the exposed groups were significantly higher (p Conclusion: This study indicated greater levels of some renal biomarkers in automobile workers compared with the controls. In addition, blood urea levels were elevated above normal range of values. These findings suggest that the occupationally exposed automobile workers may be at risk of renal diseases. This calls for urgent need for policy formulation that will prevent the vulnerable groups from kidney damage.