Contribution of Immunohistochemistry in the Diagnosis of Lymphomas

• 作者: Daouda Kone Maimouna Toure Pr Aissata Tolo Sogbety Eric Diomande Ulrich Acko Yao Nicaise Atimere Zana Ismael Coulibaly
• 来源期刊: 血液病期刊(英文)
• 学科: 医学
• 关键词: LYMPHOMAS IMMUNOHISTOCHEMISTRY HISTOLOGY WHO Classification
• 年，卷（期）: 2018,（1）
• 页码范围: 17-25
• 页数: 9页
• 分类号: R73

摘要

Objective: Making the interest of using immunohistochemistry clear in addition to histological test in the diagnosis of lymphomas. Methods: This is a retrospective study from January 2011 to June 2013 involving 18 cases of lymphomas collected in the teaching hospitals of Treichville and Yopougon. Results: 1) 38.88% diagnosis of LMNH B large-cell in histology against 38.88% LDGCB with IHC. 2) 11.11% diagnosis of LMNH small cell in histology against 11.11% with IHC. 3) 5.55% diagnosis of T lymphoma in histology against 27.77% diagnosis of T lymphoma with IHC. 4) 5.55% diagnosis of follicular lymphoma in histology against 11.11% diagnosis of LF with IHC. 5) 11.11% diagnosis of Burkitt lymphoma in histology against 5.55% diagnosis of LB with IHC. 6) 5.55% diagnosis of medullary hypoplasia in histology against 5.55% diagnosis of Hodgkin’s disease. Our results confirm the contribution of immunohistochemistry in the diagnosis of lymphomas in addition to histological test. This is striking, especially as there is 27.77% of T lymphoma with immunohistochemistry against only 5.55% with histology.