Investigation of operative skills and cranioplasty complications using biomimetic bone(nano-hap/collagen composites)

• 作者: Chaoqiang Xue Lin Chen Qinglin Zhang Tuoyu Chen Xin Pan Yuqi Zhang
• 来源期刊: 临床转化神经医学(英文版)
• 学科: 医学
• 关键词: BIOMIMETIC BONE SKULL defect CRANIOPLASTY COMPLICATIONS
• 年，卷（期）: 2018,（2）
• 页码范围: 131-140
• 页数: 10页
• 分类号: R651.1

摘要

The aim of the current study was to investigate the operation skills and complications associated with skull defect repair using biomimetic bone(nano-hap/collagen composites). Clinical data from 45 patients with skull defects who underwent cranioplasty with biomimetic bone from January 2014 to January 2017 were retrospectively analyzed.All patients participated in follow-up visits from 8 months to 3 years postoperatively. Cranioplasties were successful in all 45 patients,but 17 patients(20 cases) presented various complications, including subcutaneous hydrops(14 cases), biomimetic bone fixation loosening(4 cases), wound indolence(1 case), and biomimetic bone fragmentation(1 case). Cranioplasty complications in surgeries using biomimetic bone are more common in children than in adults.Understanding the physicochemical properties of biomimetic bone and the normal developmental process in children, as well as mastering the appropriate surgical skills and implementing the effective preventive measures are all ways to reduce and control the incidence of complications associated with biomimetic bone cranioplasty.