Metals Complexes Formed with Oleanolic Acid

• 作者: Antonio J. Demuner Célia R. A. Maltha Elson A. de Alvarenga Marcelo H. dos Santos Nilton C. Ribeiro Slavko Komarnytsky
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 化学
• 关键词: Oleanolic ACID COMPLEX PCR
• 年，卷（期）: yjhxgjqkyw_2018,（1）
• 页码范围: 160-169
• 页数: 10页
• 分类号: O6

摘要

The oleanolic acid possesses diverse pharmacological properties, it is considered as a good starting material for creating new compounds. The oleanolic acid isolated of Plumeria obtusa leaves was used as raw material to obtained calcium, magnesium, zinc, nickel and copper complexes. The structures of complexes were confirmed by HRMS, 1H NMR, and 13C NMR. Five new compounds were synthesized to promote increased biological activity of oleanolic acid and PCR assays for the different type of cancer.