Why is understanding the relationship of testosterone to cardiovascular risk so important?

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2018,（2）
• 页码范围: 107-108
• 页数: 2页
• 语种: 英文

摘要

Epidemiological studies hint at a beneficial influence of endogenous circulating testosterone (T), or its metabolite dihydrotestosterone (DHT),such that men with lower concentrations of T or DHT appear to have poorer health outcomes including frailty, diabetes,cardiovascular disease, and mortality.Small interventional studies of T have shown favorable effects on surrogate outcome measures, but a large randomized controlled trial (RCT) with the prespecified outcome of cardiovascular events has not been performed and would be logistically demanding.