Yield of capsule endoscopy in obscure gastrointestinal bleeding:A comparative study between premenopausal and menopausal women

• 作者: Adélia Rodrigues Ana Ponte Catarina Gomes Jaime Pereira Rodrigues Joao Carlos Silva Joao Carvalho Mafalda Sousa Rolando Pinho
• 来源期刊: 世界胃肠内镜杂志：英文版（电子版）
• 学科: 医学
• 关键词: Diagnostic YIELD Obscure gastrointestinal BLEEDING PREMENOPAUSAL WOMEN MENOPAUSAL WOMEN Capsule endoscopy
• 年，卷（期）: 2018,（10）
• 页码范围: 301-307
• 页数: 7页
• 分类号: R

摘要

AIM to evaluate differences in capsule endoscopy(CE)performed in the setting of obscure gastrointestinal bleeding(OGIB)among premenopausal women(PMW)and menopausal women(MW).METHODS Retrospective,single-center study,including female patients submitted to CE in the setting of OGIB between May 2011 and December 2016.Patients were divided into 2 groups according to age,considering fertile age as≤55 years and postmenopausal age as>55 years.The diagnostic yield(DY),the rebleeding rate and the time to rebleed were evaluated and compared between groups.Rebleeding was defined as a drop of Hb>2 g/dL or need for transfusional support or presence of melena/hematochezia.RESULTS A hundred and eighty three female patients underwent CE for OGIB,of whom 30.6%(n=56)were PMW and 69.4%(n=127)were MW.The DY was 30.4%in PMW and 63.8%in MW.The most common findings were angiodysplasias in both groups(PMW:21.4%,MW:44.9%)(P=0.003).In PMW,only 1.8%required therapeutic endoscopy.In 17.3%of MW,CE findings led to additional endoscopic treatment.Rebleeding at 1,3 and 5 years in PMW was 3.6%,10.2%,10.2%and 22.0%,32.3%and 34.2%in MW.Postmenopausal status was significantly associated with higher DY(P<0.001),TY(P=0.003),rebleeding(P=0.031)and lower time to rebleed(P=0.001).CONCLUSION PMW with suspected OGIB are less likely to have significant findings in CE.In MW DY,need for endoscopic treatment and rebleeding were significantly higher while time to rebleed was lower.