Observation of Stereotactic Radiosurgery (Cyberknife) on Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis

• 作者: Tang Yang
• 来源期刊: 临床护理研究
• 学科: 医学
• 关键词: hepatocellular carcinoma PORTAL VEIN tumor THROMBOSIS STEREOTACTIC RADIOSURGERY efficacy
• 年，卷（期）: lchlyj_2018,（4）
• 页码范围: 1-4
• 页数: 4页
• 分类号: R73

摘要

The purpose of the study was to analyze the clinical effect of stereotactic radiosurgery(SRS)(Cyberknife)on hepatocellular carcinoma with portal vein tumor thrombosis(HCC-PVTT).Data from 50 patients with HCC-PVTT who received Cyberknife from August 2013 to April 2016 was collected for efficacy analysis.Moreover,survival correlation was evaluated by Cox proportionalhazards model.The total effective rate in 1-3 months after treatment was 64.00%,including 7 cases in complete remission,12 cases in partial remission,13 cases in stable conditions,and 18 cases with enlargement;a 4-24-months follow-up(with an average of 11.58±2.58 months)showed that median survival,1-year cumulative survival rate,and 2-year cumulative survival rate were,respectively,11.86±1.79 months,48.00%,and 20.00%.Moreover,the Cox proportional-hazards model indicates that it was with no correlation between lesion diameter,classification of liver function,pre-operative alphafetoprotein,types of hepatitis,number of tumors,ascites,types of tumor emboli,total dose,and survival rate.SRS is effective for HCC-PVTT and serves as an ideal treatment clinically to help preserve patients’lives,which is worthy of clinical promotion and application.