Update on Gastric Cancer Epidemiology and Risk Factors

• 作者: Adil Ibrahimi Adil Najdi Dafr Allah Benajah Mohammed El Abkari Mounia El Yousf Nada Lahmidani Naoufal Mellas Nourdine Aqodad Zineb Benbrahim
• 来源期刊: 癌症治疗(英文)
• 学科: 医学
• 关键词: ADENOCARCINOMA Gastric INCIDENCE Risk Factors HELICOBACTER PYLORI
• 年，卷（期）: 2018,（3）
• 页码范围: 242-254
• 页数: 13页
• 分类号: R73

摘要

Gastric adenocarcinoma is the most common gastric tumor. It is the fifth most common cancer worldwide after lung cancer, breast, colo rectal and prostate cancer. Long considered enigmatic, its epidemiology has changed over time. In fact, the incidence of distal gastric cancer has declined while that of the cardia was stable or increased. This cancer is multifactorial but reducing the incidence of distal cancer is particularly attributed to advances in the treatment of H. pylori infection. In this review, we analyzed the available data concerning the changing epidemiology of gastric cancer and the main risk factors. The incidence of distal cancer is definitely declining due to the control of Helicobacter pylori infection. Proximal gastric cancer and cardia cancer is particularly due to smoking, overweight.