The main requirements for current medical practice include the ability to solve complex medical problems and to handle medical devices.As a result,graduates of medicine are expected to have an adequate level of physical and technical literacy.The aim of our study was to find out how students of medicine,after completing the subject Biophysics,solve a model problem from medical practice and the factors that can affect the correctness of their solution.One hundred and twenty-nine students were asked to respond to the following problem:“At first sight,a stethoscope appears to be in good condition(bell,diaphragm,and transfer system)but you do not hear anything during auscultation.Give reasons.”All of the answers were categorised and evaluated quantitatively and qualitatively.The students were not able to comprehensively solve this problem.They relied on their knowledge of the methodology of measurement rather than on the physical principles of the medical device.The solutions significantly depended on gender and their experience before entering medical school.Therefore,we propose the use of problem-based learning that focuses on real practice problems in the teaching process at schools of all levels.Implementing this method of teaching over the long-term will enable students to find the right algorithm for problem-solving.