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摘要:
Hepatitis C is a major risk factor for the development of hepatocellular carcinoma (HCC), arising typically on a background of liver cirrhosis. Treatment of hepatitis C has been revolutionized by the addition of oral direct-acting antivirals (DAAs) with sustained virological response (SVR) rates above 90%. There is a recent concern under debate about the increased risk of early HCC recurrence in patients with chronic hepatitis C who were treated with direct-acting antivirals. Nonetheless, these reports mostly focused on patients who were cirrhotic and were already treated for HCC. We report 4 cases of treatment naive, chronic hepatitis C patients who were treated with DAAs and rapidly developed infiltrative HCC despite achieving SVR. Moreover, in our scenario, one of the patients appeared clinically non-cirrhotic until he developed HCC.
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文献信息
篇名 Rapid Development of Hepatocellular Carcinoma after Eradication of Hepatitis C Virus with Directly Acting Antiviral Treatment
来源期刊 肠胃病学期刊(英文) 学科 医学
关键词 Direct ACTING ANTIVIRALS Hepatitis C Hepatocellular Carcinoma HEPATOMA
年,卷(期) 2018,(9) 所属期刊栏目
研究方向 页码范围 295-305
页数 11页 分类号 R5
字数 语种
DOI
五维指标
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研究主题发展历程
节点文献
Direct
ACTING
ANTIVIRALS
Hepatitis
C
Hepatocellular
Carcinoma
HEPATOMA
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
肠胃病学期刊(英文)
月刊
2163-9450
武汉市江夏区汤逊湖北路38号光谷总部空间
出版文献量(篇)
108
总下载数(次)
0
总被引数(次)
0
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