Contrast uptake in primary hepatic angiosarcoma on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging in the hepatobiliary phase

• 作者: Atsushi Takahashi Hirofumi Sekino Hiromasa Ohira Hiroshi Ito Kazumichi Abe Ken Okai Manabu Hayashi Masahito Kashiwagi Naoki Matsuoka Satoshi Kawana Yukiko Kanno Yuko Hashimoto
• 来源期刊: 世界肝病学杂志：英文版（电子版）
• 学科: 医学
• 关键词: Hepatic ANGIOSARCOMA Gadoliniumethoxybenzyl-diethylenetriamine pentaacetic acid Cirrhosis Hepatocellular carcinoma
• 年，卷（期）: 2018,（1）
• 页码范围: 166-171
• 页数: 6页
• 分类号: R

摘要

Primary hepatic angiosarcoma is the most common malignant mesenchymal tumor of the liver.It has a poor prognosis and various appearances on magnetic resonance(MR)images.We report a case of hepatic angiosarcoma with a characteristic appearance on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid(Gd-EOB-DTPA)-enhanced MR imaging in the hepatobiliary phase.A 72-year-old man was admitted with a complaint of abdominal pain.Gd-EOBDTPA-enhanced MR imaging revealed a liver tumor that showed slight hyperintensity in the hepatobiliary phase.These findings suggested Gd-EOB-DTPA uptake in the tumor.An autopsy revealed the solid proliferation and sinusoidal spreading of hepatic angiosarcoma cells.Immunohistochemistry indicated that the tumor was negative for OATP1B3.Gd-EOB-DTPA uptake in the liver tumor in the hepatobiliary phase suggested sinusoidal tumor invasion with residual normal hepatocytes.