A mechanism of nitric oxide regulation in high-altitude Tibetans

• 来源期刊: 国家科学评论（英文版）
• 年，卷（期）: 2018,（4）
• 页码范围: 531
• 页数: 1页
• 语种: 英文
• DOI: 10.1093/nsr/nwy040

摘要

In the paper of He et al.[1],the authors unveiled an important mechanism of nitric oxide regulation in Tibetans under high-altitude hypoxia,which might be valuable in understanding the altitudinal adaption of Tibetan people.In particular,the authors overturned the previous proposal of a Tibetan-specific NOx up-regulation as an adaptive strategy to high-altitude hypoxia and proposed that the NOx up-regulation is probably a common physiological response to hypoxia for general populations,including both Tibetan and Han Chinese.I am convinced by many lines of evidence presented in the manuscript and I would like to commend the authors for an inspiring paper.