Lipophagy is essential for lipid metabolism in fish

• 来源期刊: 科学通报（英文版）
• 年，卷（期）: 2018,（14）
• 页码范围: 879-882
• 页数: 4页
• 语种: 英文

摘要

Lipophagy is a form of autophagy in mammals. In this cellular process, lipid droplets (LDs) are degraded through the lysosomal degradative pathway [1]. During lipophagy, LDs sequestrated in autophagosomes are delivered to lysosomes, which fuse to form autophagosomes and then develop into autophagolysosomes, leading to LDs degradation of [1]. A number of studies have demonstrated that lipophagy play important roles in lipid metabolism and energy homeostasis in mammals [1-3]. However, studies about the existence and biological functions of lipophagy in other organisms have been very limited until now.