双调蛋白及其在气道炎性疾病中作用的研究进展

• 作者: 许昱 高玲
• 来源期刊: 临床耳鼻咽喉头颈外科杂志
• 学科: 医学
• 关键词: 双调蛋白 气道炎性疾病
• 年，卷（期）: 2018,（1）
• 所属期刊栏目: 综述
• 页码范围: 77-80
• 页数: 4页
• 分类号: R764
• 语种: 中文
• DOI: 10.13201/j.issn.1001-1781.2018.01.016

摘要

Amphiregulin is a member of epidermal growth factor family,and is also one of the ligand of epidermal growth factor receptor,it participates in many physiological and pathological process by combining with EGFR.Researches have proved that AREG participates in asthma and airway inflammatory diseases caused by smoking and PM 2.5,and AREG plays an important role in the process of airway remodeling and inflammation.This paper mainly reviews the expression and function of AREG,and focus on it's research status in airway inflammatory disease.