A male patients at 11 years of age, was hospitalized for the right ear pain and mouth deviation for five days on August 30, 2016, accompanied by right hypophasis, right ear hearing loss, tinnitus, without otorrhea and vertigo.Patient was diagnosed as acute promyelocytic leukemia in 2008.After standardized chemotherapy, it was completely relieved and the blood and bone marrow images were almost restored to normal.Physical examination:The skin of the right external auditory canal is obviously swollen, without rupture on the surface, and the tympanic membrane cannot be seen.The drooping of the left angle of the mouth, the right eyelid is not closed completely, the right nasolabial groove and forehead line is shallower.House-Brackmann facial nervous systemⅢ.Routine blood:the leucocyte 10.31×109/L, more than in the normal range.Pure tone measurement showed that right ear conductive deafness, air-bone conduction difference of each frequency range 50 to 75 dB.Mastoid CT showed that right mastoid gasification is good, the right external auditory canal, middle ear cavity and mastoid airway are filled with low-density soft tissue shadows, the bone wall of the external auditory canal was not significantly enlarged or damaged.The auditory bone is intact, surrounded by a large number of soft tissue shadows, no obvious abnormalities in the inner ear.Primary diagnosis:Middle ear cholesteatoma (right);External auditory canal tumor (right);Peripheral facial paralysis (right).