Studies and Mechanism of Olefination Reaction in Aryl-Enolates with Paraformaldehyde

• 作者: Jaime Escalante Jonathan Román Valdéz-Camacho José Domingo Rivera-Ramírez
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 化学
• 关键词: OLEFINATION PARAFORMALDEHYDE α-Aryl-α β-Unsaturated Ester α-Methylenation
• 年，卷（期）: yjhxgjqkyw_2019,（1）
• 页码范围: 10-22
• 页数: 13页
• 分类号: O6

摘要

A simple, efficient and low-cost methodology for the synthesis of α-aryl-α,β-unsaturated esters using paraformaldehyde as a source of carbon was developed. Factors that control reaction yields such as temperature, concentration and reaction time were evaluated. A mechanism is proposed based on experimental structures of the intermediates.