Sodium ion channels are the main activation of electrical signals,which are the basis of a series of physiological processes such as nerve activity and muscle contraction of excitable cells.Traditional Chinese medicine(TCM)has a history of more than 2000 years,and there are more and more researches about TCM on sodium ion channels.This article summarized these researches and had a prospect on its future as well as the next possible focuses in order to lay a foundation for the modern pharmacology and development and promotion of TCM.