With the development of science and technology, informationization and economic globalization are developing faster and faster, and their impact on the world's economy and trade is also growing. The United States started the rebalancing strategy with tax reform as the starting point, and had large-scale trade frictions with China. How to avoid economic and trade frictions and promote sustainable economic development has become an important issue facing all countries. Although the economic and trade relations between the two countries are generally in a stable state, the friction in the trade field between the two countries exists in every stage of their economic and trade cooperation from beginning to end. The occurrence of trade friction not only affects the development of bilateral trade and regional economic development, but also may lead to a worldwide economic crisis. This paper analyzes the new forms of trade friction faced by the two countries under economic globalization through the friction between China and the United States in trade. With a view to promoting the sound development of trade between the two countries.