In recent years,through the study of tumor microenvironment,it is found that inflammation plays an important role in the occurrence of tumors.The relationship between inflammation and tumors is becoming more and more clear:the long-term existence of uncontrollable inflammation can promote tumors.The occurrence of the tumor microenvironment formed by the tumor and other surrounding cells also promotes further uncontrolled development of inflammation.Based on the relationship between inflammation and tumor microenvironment,this paper describes the tumor microenvironment and its characteristics,the role of several major mediators in inflammation on tumors,and provides a new strategy for the precise immunotherapy of tumors.